Boston Planning & Development Agency officials are going on the record with opposition to a planned Amazon last-mile distribution center on Dorchester Avenue in South Boston.

The project is inconsistent with the BPDA’s South Boston Dorchester Ave. study, BPDA directors stated in recommending the zoning board of appeals reject the developer’s petition without prejudice. The multi-year planning study was a guideline for transforming the neighborhood from a hodgepodge of industrial uses into higher-density development including office space and “21st-century industrial” uses.

In May, developers unveiled plans for an Amazon last-mile distribution center on a portion of the 22-acre site near Andrew station on the MBTA Red Line, currently used for parking and storage.

An affiliate of Boston-based Core Investments seeks to demolish a pair of industrial buildings on Dot Ave. and Alger Street and renovate a former Blue Cross Blue Shield warehouse for the Amazon facility, while using another section of the property for vehicle storage.

A zoning board of appeals hearing is scheduled for Nov. 17 on a petition to maintain the existing vehicle storage on the property and add surface parking for commercial delivery vans as a use for the property.

Core Development has said the distribution center would be the first phase of “On the Dot,” a longer-term mixed-use project spanning up to 8 million square feet.

The site runs for a half-mile along Dorchester Avenue, where major developers have acquired a series of industrial parcels between Andrew and Broadway stations for redevelopment as housing and retail uses.

In a spring presentation to a neighborhood association, developers said Amazon delivery vans would depart in 20-minute intervals during off-peak traffic hours.

BPDA planning studies have identified the South Boston Dot Ave. corridor as a key potential growth area because of its Red Line access and proximity to downtown and future development sites such as Widett Circle.