Two separate biotechnology companies have signed leases for Walden Square Science Center at 85 Bolton St. in Cambridge.

Tetragenetics Inc. leased 9,000 square feet on the second floor of Walden Square Science Center, according to a statement. Cushman & Wakefield represented Tetragenetics in the lease transaction.

Ligon Discovery Inc. leased 2,500 square feet on the first floor of Walden Square Science Center. Boston’s Newmark Knight Frank represented Ligon Discovery Inc. in the lease transaction.

Ryan Weber and Christopher McMahon, senior managing directors at Newmark Knight Frank, represented the landlord Bolton Street LLC in both lease transactions.