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Industrial parcels on the far reaches of the Seaport District are due for their first major changes in decades with development plans being drawn up by Oxford Property Group.

The Canadian real estate investor is teaming up with Pappas Enterprises on up to 1.7 million square feet of proposed development on nearly 8 acres of land along West First Street, Pappas Way and the Reserved Channel waterway.

The project would replace existing industrial buildings and parking lots with seven buildings including unspecified commercial uses, a neighborhood grocery store and an unspecified amount of housing, developers said in a notification letter submitted to the Boston Planning & Development Agency.

The largest share of the new development – at 1.1 million square feet – would be located along West First Street.

The building heights will reflect the existing buildings along First Street and nearby residential neighborhoods in South Boston, Oxford Properties’ Mark McGowan and Pappas Enterprises’ Timothy Pappas said in the filing.

The site includes 6.2 acres that Pappas Enterprises ground-leases from Massport and another 1.7 acres owned by Oxford. The two companies formed a joint venture in 2019 for the Pappas-owned parcels, developers said.

Developers will seek approval under a planned development area process, which provides zoning relief for larger sites.

The proposal follows a recent proposal for a 99,000-square-foot life science building at 6 Elkins St. on the opposite side of the Reserved Channel, and a Connecticut developer’s acquisition of a nearby Greyhound bus yard that had been marketed as a multifamily development site.