Three developers with experience on large commercial projects in Boston and Cambridge are in the running to partner with Harvard University on its Enterprise Research Campus in Allston.

HYM Investment Group, a partnership of life science specialist Alexandria Real Estate Equities and National Development, and a partnership of Tishman Speyer and Bellco Capital called Breakthrough Properties will vie for the rights to build the new mixed-use development on Western Avenue. The finalists were first reported by The Boston Globe.

“Harvard Allston Land Co. was incredibly pleased with the responses from all of the finalists and is excited to move forward to the final round with three development teams. The board remains deeply engaged in the ongoing selection process, working toward the goal of selecting a partner by the end of the year,” CEO Tom Glynn said in a statement.

In October, Harvard Allston Land Co. selected nine semifinalists as it seeks a partner on development of 14 acres across from Harvard Business School. The university plans to build 400,000 square feet of office and lab space, a 250,000-square-foot hotel and conference center and 250,000 square feet of residential space.

The commercial component is designed to enhance Harvard’s partnerships with private companies, with part of the office and lab space allocated to local startups.

The 14-acre first phase is part of 36 acres that Harvard owns that can be developed before the Massachusetts Department of Transportation begins the Massachusetts Turnpike realignment project, which will free up additional land for Harvard to develop as the highway is straightened and moved south to the former CSX rail yards.

This report has been updated with a statement from Harvard Allston Land Co. CEO Tom Glynn.