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A major commercial landlord in Harvard and Davis squares has landed another top-shelf local portfolio.

Asana Partners has acquired the Newbury Collection, an assemblage of 28 Back Bay buildings totaling 220,000 square feet, for $297.9 million.

The company has targeted acquisitions of high-profile retail properties in Greater Boston in recent years. The Charlotte-based company was founded in 2015 by a group of former executives from South Carolina developer Edens, which owns Boston’s South Bay Center and the Woburn Mall.

Eastdil represented the seller, Atlanta-based Jamestown, which paid $226 million for the Newbury Collection in 2011. Hartford Fire Insurance Co. provided $165 million in mortgage financing.

CBRE/New England has been hired as retail leasing agent by the new owners.

The portfolio includes 71 Newbury St., 81 Newbury St., 85-91 Newbury St., 119 Newbury Street, condo units at 144 Newbury St., 265-275 Dartmouth St., 154-156 Newbury St., 160 Newbury St., 172 Newbury St., 177 Newbury St., 179 Newbury St., 220 Newbury St., 234-236 Clarendon St., 234-236 Newbury St., 283 Dartmouth St., 286-288 Newbury St., 299-301 Newbury St., 329 Newbury St., 899 Boylston St., 111-115 Newbury St., 127 and 129 Newbury St. and 328 Newbury St.

Asana acquired 240 Elm St., a retail and office property in Somerville’s Davis Square that’s anchored by bfresh grocery, for $39 million in September. That transaction, at $842 per square foot, was Greater Boston’s highest-priced retail transaction of 2018, according to Avison Young research. In late 2017, Asana acquired the nearly 62,000-square-foot Brattle Court portfolio including Cardullo’s Gourmet Shop in Harvard Square for $108 million late last year.

Asana executives were not available for comment.