Boston-based Longfellow Real Estate Partners has raised $500 million in a new fund that will acquire tech and life science properties across the U.S.

The new Longfellow Strategic Value Fund will acquire stabilized assets, conversions for lab and tech uses and ground-up development, the company announced this week. The fund will focus on investments in innovation and knowledge industry clusters.

Hodes Weill Securities LLC acted as the exclusive financial advisor and placement agent to Longfellow.

Led by managing partners Adam Sichol and Jamie Peschel, Longfellow has acquired more than 2 million square feet of commercial real estate with a focus on the life science segment. It’s one of a dozen developers that responded in May to Massport’s request for proposals to develop a 550,000-square-foot office building on parcel A-2 on Congress Street in Boston’s Seaport District.

Longfellow last year acquired three office buildings in the Alewife section of Cambridge for $370.2 million in a partnership with Morgan Stanley, with Longfellow acting as operating partner.